Predicting the onset of Alzheimer's disease with a behavioral task

  title={Predicting the onset of Alzheimer's disease with a behavioral task},
  author={S. Zola and C. Manzanares and A. Levey and J. Lah},
  journal={Alzheimer's & Dementia},
  • S. Zola, C. Manzanares, +1 author J. Lah
  • Published 2011
  • Medicine
  • Alzheimer's & Dementia
  • mentia in 2 years. Results: 62 (33%) of the subjects with aMCI (age1⁄469.5 (SD 7.9), MMSE1⁄426.4 (2.6)) and 23 (19%) subjects with naMCI (age1⁄470.0 (7.3), MMSE1⁄427.5 (2.1)) converted to AD-type dementia after an average follow up of 1.6 years (SD 0.6). The odds ratio of the CSF Ab1-42/tau ratio, hippocampal volume and APOE-34 genotype for AD-type dementia was similar in each MCI subgroup. However, the sensitivity, specificity and positive predictive value varied between MCI subgroups (see… CONTINUE READING
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