• Corpus ID: 208526862

Predicting skull lesions after clinical transcranial MRI-guided focused ultrasound with acoustic and thermal simulations

  title={Predicting skull lesions after clinical transcranial MRI-guided focused ultrasound with acoustic and thermal simulations},
  author={Nathan J. McDannold and Phillip Jason White and Rees G. Cosgrove},
  journal={arXiv: Medical Physics},
Transcranial MRI-guided focused ultrasound (TcMRgFUS) thermal ablation is a noninvasive functional neurosurgery technique. Previous reports have shown that bone marrow damage in the skull can occur at high acoustic energies. While this damage is asymptomatic, it would be desirable to avoid it. Here we examined whether acoustic and thermal simulations can predict where the thermal lesions in the skull might occur. Post-treatment imaging was obtained at 3-15 months after 40 clinical TcMRgFUS… 

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