Predicting risk of adverse drug reactions in older adults.

  title={Predicting risk of adverse drug reactions in older adults.},
  author={Amanda Hanora Lavan and Paul Francis Gallagher},
  journal={Therapeutic advances in drug safety},
  volume={7 1},
Adverse drug reactions (ADRs) are common in older adults, with falls, orthostatic hypotension, delirium, renal failure, gastrointestinal and intracranial bleeding being amongst the most common clinical manifestations. ADR risk increases with age-related changes in pharmacokinetics and pharmacodynamics, increasing burden of comorbidity, polypharmacy, inappropriate prescribing and suboptimal monitoring of drugs. ADRs are a preventable cause of harm to patients and an unnecessary waste of… CONTINUE READING
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