Predicting protein sumoylation sites from sequence features

@article{Teng2011PredictingPS,
  title={Predicting protein sumoylation sites from sequence features},
  author={Shaolei Teng and Hong Luo and Liangjiang Wang},
  journal={Amino Acids},
  year={2011},
  volume={43},
  pages={447-455}
}
Protein sumoylation is a post-translational modification that plays an important role in a wide range of cellular processes. Small ubiquitin-related modifier (SUMO) can be covalently and reversibly conjugated to the sumoylation sites of target proteins, many of which are implicated in various human genetic disorders. The accurate prediction of protein sumoylation sites may help biomedical researchers to design their experiments and understand the molecular mechanism of protein sumoylation. In… 
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TLDR
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The signal crosstalk between SUMOylation and ubiquitination of proteins, protein SUMOolation relations with several diseases, and the identification approaches for SUMOYLation site are discussed.
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