Predicting protein-protein interactions in unbalanced data using the primary structure of proteins

@inproceedings{Yu2009PredictingPI,
  title={Predicting protein-protein interactions in unbalanced data using the primary structure of proteins},
  author={Chi-Yuan Yu and Lih-Ching Chou and Darby Tien-Hao Chang},
  booktitle={BMC Bioinformatics},
  year={2009}
}
Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles of biological systems. Previous studies have revealed that interacting protein pairs can be predicted by their primary structure. Most of these approaches have achieved satisfactory performance on datasets comprising equal number of interacting and non-interacting protein pairs. However, this ratio is highly unbalanced in nature… CONTINUE READING
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