Predicting patterns of long‐term adaptation and extinction with population genetics

@article{Bertram2017PredictingPO,
  title={Predicting patterns of long‐term adaptation and extinction with population genetics},
  author={Jason Bertram and Kevin Gomez and Joanna Masel},
  journal={Evolution},
  year={2017},
  volume={71}
}
Population genetics struggles to model extinction; standard models track the relative rather than absolute fitness of genotypes, while the exceptions describe only the short‐term transition from imminent doom to evolutionary rescue. But extinction can result from failure to adapt not only to catastrophes, but also to a backlog of environmental challenges. We model long‐term adaptation to long series of small challenges, where fitter populations reach higher population sizes. The population's… 
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