Predicting new molecular targets for known drugs

Abstract

Although drugs are intended to be selective, at least some bind to several physiological targets, explaining side effects and efficacy. Because many drug-target combinations exist, it would be useful to explore possible interactions computationally. Here we compared 3,665 US Food and Drug Administration (FDA)-approved and investigational drugs against… (More)
DOI: 10.1038/nature08506

Topics

3 Figures and Tables

Blog articles referencing this paper

Slides referencing similar topics