Predicting meiotic pathways in human fetal oogenesis.

  title={Predicting meiotic pathways in human fetal oogenesis.},
  author={Ping Zheng and Michael D Griswold and Terry J. Hassold and Patricia A Hunt and Christopher L. Small and Ping Ye},
  journal={Biology of reproduction},
  volume={82 3},
Gene function prediction has proven valuable in formulating testable hypotheses. It is particularly useful for exploring biological processes that are experimentally intractable, such as meiotic initiation and progression in the human fetal ovary. In this study, we developed the first functional gene network for the human fetal ovary, HFOnet, by probabilistically integrating multiple genomic features using a naïve Bayesian model. We demonstrated that this network could accurately recapture… CONTINUE READING