Predicting ischemic heart disease in women: the value of endothelial function.

@article{Lian2010PredictingIH,
  title={Predicting ischemic heart disease in women: the value of endothelial function.},
  author={Bill Q. Lian and John F. Keaney},
  journal={Journal of the American College of Cardiology},
  year={2010},
  volume={55 16},
  pages={1697-9}
}
ince the discovery in 1980 that acetylcholine elicits vasoilation in an endothelium-dependent manner (1), it has ecome evident that the endothelium plays a crucial role in ascular homeostasis by regulating vasodilation, smooth uscle cell proliferation and migration, platelet and leukoyte adhesion, and thrombosis. Endothelial dysfunction is haracterized by the impairment of endothelium-dependent asodilation due to reduced vasodilator bioactivity, particuarly nitric oxide (NO), and/or an increase… CONTINUE READING
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