Predicting different adhesive regimens of circulating particles at blood capillary walls

  title={Predicting different adhesive regimens of circulating particles at blood capillary walls},
  author={Alessandro Coclite and Hilaria Mollica and Sergio Ranaldo and Giuseppe Pascazio and Marco D. de Tullio and Paolo Decuzzi},
  journal={Microfluidics and Nanofluidics},
A fundamental step in the rational design of vascular targeted particles is the firm adhesion at the blood vessel walls. Here, a combined lattice Boltzmann–immersed boundary model is presented for predicting the near-wall dynamics of circulating particles. A moving least squares algorithm is used to reconstruct the forcing term accounting for the immersed particle, whereas ligand-receptor binding at the particle–wall interface is described via forward and reverse probability distributions… 

Vascular journey and adhesion mechanics of micro-sized carriers in narrow capillaries.

  • A. Coclite
  • Materials Science
    Microvascular research
  • 2020

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