Predicting caffeine plasma concentrations resulting from consumption of food or beverages: a simple method and its origin.

@article{Pfeifer1988PredictingCP,
  title={Predicting caffeine plasma concentrations resulting from consumption of food or beverages: a simple method and its origin.},
  author={Renate Pfeifer and Robert E. Notari},
  journal={Drug intelligence & clinical pharmacy},
  year={1988},
  volume={22 12},
  pages={953-9}
}
Multiple dosage regimens for therapeutic agents are commonly comprised of a constant dosing interval and a constant dose size. This is not true for the ingestion of a pharmacologically active agent that is a component in a dietary source. Caffeine is contained in foods and beverages that are regular components of the diet for many people. Because daily intake is unsystematic, a computer program was written to simulate caffeine plasma concentration-time courses following ingestion of variable… CONTINUE READING