Predicting beta-interferon failure in relapsing-remitting multiple sclerosis.

@article{ORourke2007PredictingBF,
  title={Predicting beta-interferon failure in relapsing-remitting multiple sclerosis.},
  author={Killian E T O'Rourke and Cathal Walsh and G. Giovanni Antonelli and Michael Hutchinson},
  journal={Multiple sclerosis},
  year={2007},
  volume={13 3},
  pages={
          336-42
        }
}
Proposed beta-interferon (IFNbeta) treatment failure criteria for patients with relapsing-remitting multiple sclerosis (RRMS) have not been validated in clinical practice. This study aimed to establish (a) whether IFNbeta attenuated accumulation of fixed disability in comparison to a cohort of matched historical control subjects from the Sylvia Lawry centre for MS research, and (b) whether relapse-based treatment failure criteria or clinical and demographic variables had predictive value for… CONTINUE READING
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