Predicting a local recurrence after breast-conserving therapy by gene expression profiling

  title={Predicting a local recurrence after breast-conserving therapy by gene expression profiling},
  author={Dimitry S. A. Nuyten and Bas Kreike and Augustinus A. M. Hart and Jen-Tsan A. Chi and Julie B Sneddon and L. F. A. Wessels and Hans J Peterse and Harry Bartelink and Patrick O. Brown and Howard Y Chang and Marc Joan Van de Vijver},
  journal={Breast Cancer Research},
  pages={R62 - R62}
To tailor local treatment in breast cancer patients there is a need for predicting ipsilateral recurrences after breast-conserving therapy. After adequate treatment (excision with free margins and radiotherapy), young age and incompletely excised extensive intraductal component are predictors for local recurrence, but many local recurrences can still not be predicted. Here we have used gene expression profiling by microarray analysis to identify gene expression profiles that can help to predict… CONTINUE READING
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A geneexpression signature as a predictor of survival in breast cancer

  • MJ van de Vijver, YD He, +7 authors MJ Marton
  • N Engl J Med
  • 2002
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