Predicting Signatures of “Synthetic Associations” and “Natural Associations” from Empirical Patterns of Human Genetic Variation

Abstract

Genome-wide association studies (GWAS) have in recent years discovered thousands of associated markers for hundreds of phenotypes. However, associated loci often only explain a relatively small fraction of heritability and the link between association and causality has yet to be uncovered for most loci. Rare causal variants have been suggested as one… (More)
DOI: 10.1371/journal.pcbi.1002600

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Cite this paper

@inproceedings{Chang2012PredictingSO, title={Predicting Signatures of “Synthetic Associations” and “Natural Associations” from Empirical Patterns of Human Genetic Variation}, author={Diana Chang and Alon Keinan}, booktitle={PLoS Computational Biology}, year={2012} }