Predicting Pol II promoter sequences using transcription factor binding sites.

  title={Predicting Pol II promoter sequences using transcription factor binding sites.},
  author={D. S. Prestridge},
  journal={Journal of molecular biology},
  volume={249 5},
A computer program, PROMOTER SCAN, has been developed to recognize a high percentage of Pol II promoter sequences while allowing only a small rate of false positives. A total of 167 primate Pol II promoter sequences, obtained from the Eukaryotic Promoter Database, and 999 primate non-promoter sequences, obtained from the GenBank sequence databank, were used in the analysis. Both promoter and non-promoter sequences were analyzed for the comparative density of each unique mammalian transcription… CONTINUE READING
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