Predicting Pathological Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Using 18FDG-PET/CT

@article{Shanmugan2012PredictingPR,
  title={Predicting Pathological Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer Using 18FDG-PET/CT},
  author={Skandan Shanmugan and Rodrigo Arrangoiz and James R. Nitzkorski and Jian Qin Michael Yu and Tianyu Li and Harry Stanley Cooper and Andre A. Konski and Jeffrey M. Farma and Elin Ruth Sigurdson},
  journal={Annals of Surgical Oncology},
  year={2012},
  volume={19},
  pages={2178-2185}
}
Pathologic complete response (pCR) after neoadjuvant chemoradiation (CRT) has been observed in 15–30% of patients with locally advanced rectal cancer (LARC). The objective of this study was to determine whether PET/CT can predict pCR and disease-free survival in patients receiving CRT with LARC. This is a retrospective review of patients with EUS-staged T3–T4, N + rectal tumors treated with CRT, who underwent pre/post-treatment PET/CT from 2002–2009. All patients were treated with CRT and… CONTINUE READING
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