Predicting Optimal DEER Label Positions to Study Protein Conformational Heterogeneity.

@article{Mittal2017PredictingOD,
  title={Predicting Optimal DEER Label Positions to Study Protein Conformational Heterogeneity.},
  author={Shriyaa Mittal and Diwakar Shukla},
  journal={The journal of physical chemistry. B},
  year={2017},
  volume={121 42},
  pages={9761-9770}
}
Double electron-electron resonance (DEER) spectroscopy is a powerful experimental technique for understanding the conformational heterogeneity of proteins. It involves attaching nitroxide spin labels to two residues in the protein to obtain a distance distribution between them. However, the choice of residue pairs to label in the protein requires careful… CONTINUE READING