Predicting Controlled-Release Behavior of Degradable PLA-b-PEG-b-PLA Hydrogels

@inproceedings{Mason2001PredictingCB,
  title={Predicting Controlled-Release Behavior of Degradable PLA-b-PEG-b-PLA Hydrogels},
  author={Mariah N. Mason and Andrew T. Metters and Christopher N Bowman and Kristi S Anseth},
  year={2001}
}
This paper describes the development and application of scaling laws relating bulk-degradation behavior of poly(lactic acid)−poly(ethylene glycol)−poly(lactic acid) (PLA-b-PEG-b-PLA) copolymer hydrogels to the ever-changing transport properties during network degradation. Specifically, the relationships developed were used to extend previous work and to predict the effects of cross-linking density and hydrolytic degradation rate on the controlled release of high molecular weight proteins from… CONTINUE READING

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