Predicted creatinine clearance to assess glomerular filtration rate in chronic renal disease in humans.

@article{deSanto1991PredictedCC,
  title={Predicted creatinine clearance to assess glomerular filtration rate in chronic renal disease in humans.},
  author={N G deSanto and S. Coppola and Pietro Anastasio and Giorgio Coscarella and Giovambattista Capasso and Luigi Bellini and Rosaria Santangelo and L. Massimo and Antonella Siciliano},
  journal={American journal of nephrology},
  year={1991},
  volume={11 3},
  pages={181-5}
}
The work was designed to assess the suitability of both measured endogenous creatinine clearance (CCR) and predicted creatinine clearance (P-CCR) to evaluate GFR in chronic renal disease (CRD) by utilizing the renal clearance of inulin (CIN) as gold standard. A total of 124 subjects were studied (62 healthy, 62 with CRF). CCR significantly overestimated GFR in healthy subjects as well as in CRF, whereas P-CCR was identical to GFR. The CCR/CIN ratio which calculates the fractional creatinine… CONTINUE READING

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