Predictability of the t(1;19)(q23;p13) from surface antigen phenotype: implications for screening cases of childhood acute lymphoblastic leukemia for molecular analysis: a Pediatric Oncology Group study.

Abstract

The t(1;19)(q23;p13) translocation occurs in approximately 5% of B-precursor acute lymphoblastic leukemias (ALLs) occurring in children. Its presence has been associated with a poor prognosis, which may be overcome with more intensive therapy. Although leukemic cells from cases of t(1;19)-ALL frequently express cytoplasmic mu heavy chains, their complete… (More)

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@article{Borowitz1993PredictabilityOT, title={Predictability of the t(1;19)(q23;p13) from surface antigen phenotype: implications for screening cases of childhood acute lymphoblastic leukemia for molecular analysis: a Pediatric Oncology Group study.}, author={M J Borowitz and S P Hunger and A. J. Carroll and J J Shuster and D. Jeanette Pullen and C. Philip Steuber and Michael L. Cleary}, journal={Blood}, year={1993}, volume={82 4}, pages={1086-91} }