Predictability and randomness of paw choices are critical elements in the behavioural plasticity of mouse paw preference

@article{Ribeiro2014PredictabilityAR,
  title={Predictability and randomness of paw choices are critical elements in the behavioural plasticity of mouse paw preference},
  author={A. Ribeiro and B. Eales and J. Lloyd-Price and F. Biddle},
  journal={Animal Behaviour},
  year={2014},
  volume={98},
  pages={167-176}
}
Lateralized paw usage of mice, Mus musculus, is a learned behaviour, based on a gradual reinforcement of randomly occurring weak asymmetries in paw choice early in training. The reinforcement relies on strain-dependent, short-term and long-term memory. We characterized the skills of information accumulation by quantifying the predictability of each reach of initially naive mice from past behaviour in two training sessions of 50 reaches, separated by a 1-week interval. We studied six mouse… Expand
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References

SHOWING 1-10 OF 31 REFERENCES
Learning of paw preference in mice is strain dependent, gradual and based on short-term memory of previous reaches
We studied the dynamics of paw preference learning in unbiased symmetrical test chambers where mice, Mus musculus, could freely choose which paw to use. When compared to nonlearner model mice, threeExpand
Hand-preference training in the mouse reveals key elements of its learning and memory process and resolves the phenotypic complexity in the behaviour.
TLDR
A detailed kinetic analysis of hand-preference training in the C57BL/6J strain revealed elements of the fundamental process of learning and long-term memory that underlies the behaviour by documenting consolidation of memory, blocking of this consolidation by an inhibitor of protein synthesis, retention of memory and speed of learning in response to training reaches. Expand
Short-term and long-term memory deficits in handedness learning in mice with absent corpus callosum and reduced hippocampal commissure
TLDR
Positive autocorrelation between successive paw choices during each session and change in paw-preference bias between sessions indicate that 9XCA mice have weak, but not null, learning skills. Expand
Novelty affects paw preference performance in adult mice
The hemispheres are asymmetrically involved in the reaction to stressful situations. In this sense, it is possible to speculate that the asymmetrical activation of the hemispheres, as a result of theExpand
Mouse genetic model for left-right hand usage: context, direction, norms of reaction, and memory.
TLDR
A systematic series of tests of paw usage with naive mice and retests of the individuals in test chambers with the food tube biased to the left or to the right, contrasting the highly lateralized C57BL/6J and the very weakly lateralized (or ambilateral) CDS/Lay inbred strains and their (B6 x CDS) F1 generation resulted in an unexpected qualitative difference in paw usage. Expand
Genetic variation in paw preference (handedness) in the mouse.
TLDR
There is evidence of significant deviation of the numbers of mice to the left and right of equal paw usage, independent of degree of lateralization, and this suggests that direction of left-right paw usage may be a separate genetic trait in the mouse model. Expand
Selective Modification of Short-Term Hippocampal Synaptic Plasticity and Impaired Memory Extinction in Mice with a Congenitally Reduced Hippocampal Commissure
TLDR
Behavioral memory and hippocampal synaptic plasticity in two inbred mouse strains were characterized and the HC in mice is vital for particular aspects of memory function and for short-term synaptic modification in specific hippocampal circuits. Expand
Impaired fear memory, altered object memory and modified hippocampal synaptic plasticity in split-brain mice
TLDR
It is suggested that the increased susceptibility to DPT in BTBR may underlie the memory phenotype reported here, and it is concluded that the HC and CC are critical for some forms of hippocampal memory and for synaptic resistance to D PT. Expand
Biological Limits of Hand Preference Learning Hiding Behind the Genes
TLDR
This chapter describes hand-reaching behavior of mice and the discovery that it is a complex adaptive behavior in which future preference is genotypically dependent on past experience and defines the key elements that led to the collaborative development of a stochastic agent-based model. Expand
Dynamic Agent-Based Model of Hand-Preference Behavior Patterns in the Mouse
TLDR
It is concluded that genetically evolved hand-preference behavior in mice is inherently probabilistic to provide robustness and allow constant adaptability to ever-changing environments. Expand
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