Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning

@article{Weiss2003PrediabetesIO,
  title={Prediabetes in obese youth: a syndrome of impaired glucose tolerance, severe insulin resistance, and altered myocellular and abdominal fat partitioning},
  author={Ram Weiss and Sylvie Dufour and Sara E. Taksali and William V Tamborlane and Sonia Caprio},
  journal={The Lancet},
  year={2003},
  volume={362},
  pages={951-957}
}
BACKGROUND Impaired glucose tolerance is common among obese adolescents, but the changes in insulin sensitivity and secretion that lead to this prediabetic state are unknown. We investigated whether altered partitioning of myocellular and abdominal fat relates to abnormalities in glucose homoeostasis in obese adolescents with prediabetes. METHODS We studied 14 obese children with impaired glucose tolerance and 14 with normal glucose tolerance, of similar ages, sex distribution, and degree of… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 31 references

2000 CDC Growth Charts for the United States: methods and development.

Vital and health statistics. Series 11, Data from the National Health Survey • 2002
View 1 Excerpt

Insulin resistance in morbid obesity: reversal with intramyocellular fat depletion

A Greco, G Mingione, A Giancaterini
Diabetes 2002;51:144–51 • 2002

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