Prederivatization and high-performance liquid chromatographic analysis of alkaloids of bulbs of Fritillaria.

@article{Ding1996PrederivatizationAH,
  title={Prederivatization and high-performance liquid chromatographic analysis of alkaloids of bulbs of Fritillaria.},
  author={K. Z. Ding and G Y Lin and Yee Ping Ho and Tin Yan Cheng and Ping Li},
  journal={Journal of pharmaceutical sciences},
  year={1996},
  volume={85 11},
  pages={1174-9}
}
A method of prederivatization and HPLC with UV detection was developed for the simultaneous analysis of five major steroidal alkaloids of the Fritillaria species: verticine, verticinone, isoverticine, ebeiedine, and ebeiedinone. Derivatization was carried out by esterification of the hydroxyl-containing Fritillaria alkaloids to the corresponding naphthoates… CONTINUE READING