Precursors of Vulvovaginal Squamous Cell Carcinoma

  title={Precursors of Vulvovaginal Squamous Cell Carcinoma},
  author={Richard Oparka and Charles Simon Herrington},
The current classification of intraepithelial lesions of the vulva defines two distinct types of vulvar intraepithelial neoplasia (VIN), termed usual-type VIN (uVIN) and differentiated-type VIN (dVIN). uVIN occurs in younger women, is typically associated with high-risk HPV infection and hence with neoplasia at other anogenital sites. Vaginal intraepithelial neoplasia (VaIN) is also strongly related to HPV infection and is classified morphologically in a similar way to uVIN. Associated… CONTINUE READING
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