Precursor pools of protein synthesis: a stable isotope study in a swine model.

@article{Baumann1994PrecursorPO,
  title={Precursor pools of protein synthesis: a stable isotope study in a swine model.},
  author={Patricia Q Baumann and William S. Stirewalt and Brian O'Rourke and D. E. Howard and K. S. Nair},
  journal={The American journal of physiology},
  year={1994},
  volume={267 2 Pt 1},
  pages={
          E203-9
        }
}
The accuracy of using other free pools in lieu of tRNA for calculation of tissue protein synthesis in liver (L), skeletal muscle (SM), and heart (H) was assessed in six adult miniature swine using L-[1-13C]leucine and L-[ring-2H5]phenylalanine as tracers. L leucyl-tRNA enrichment was higher than arterial plasma leucine and ketoisocaproate (KIC) enrichments, and L phenylalanyl-tRNA enrichment was higher than arterial phenylalanine enrichment (P < 0.05). No such differences were noted in SM and H… CONTINUE READING

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