Precursor of human adenovirus core polypeptide Mu targets the nucleolus and modulates the expression of E2 proteins.

@article{Lee2004PrecursorOH,
  title={Precursor of human adenovirus core polypeptide Mu targets the nucleolus and modulates the expression of E2 proteins.},
  author={Tim W R Lee and Fiona J Lawrence and Vita Dauksaite and G{\"o}ran Akusj{\"a}rvi and G Eric Blair and David A. Matthews},
  journal={The Journal of general virology},
  year={2004},
  volume={85 Pt 1},
  pages={185-96}
}
We have examined the subcellular localization properties of human adenovirus 2 (HAdV-2) preMu and mature Mu (pX) proteins as fusions with enhanced green fluorescence protein (EGFP). We determined that preMu is exclusively a nucleolar protein with a single nucleolar accumulation signal within the Mu sequence. In addition, we noted that both preMu-EGFP and Mu… CONTINUE READING