Precursor of C4 antisense RNA of bacteriophages P1 and P7 is a substrate for RNase P of Escherichia coli.

@article{Hartmann1995PrecursorOC,
  title={Precursor of C4 antisense RNA of bacteriophages P1 and P7 is a substrate for RNase P of Escherichia coli.},
  author={Roland K. Hartmann and Janine Heinrich and J Schlegl and Heinz Schuster},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 13},
  pages={
          5822-6
        }
}
The C4 repressor of the temperate bacteriophages P1 and P7 inhibits antirepressor (Ant) synthesis and is essential for establishment and maintenance of lysogeny. C4 is an antisense RNA acting on a target, Ant mRNA, which is transcribed from the same promoter. The antisense-target RNA interaction requires processing of C4 RNA from a precursor RNA. Here we show that 5' maturation of C4 RNA in vivo depends on RNase P. In vitro, Escherichia coli RNase P and its catalytic RNA subunit (M1 RNA) can… CONTINUE READING

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