Preconditioning the human myocardium.

@article{Yellon1993PreconditioningTH,
  title={Preconditioning the human myocardium.},
  author={Derek M Yellon and Abdulaziz M Alkhulaifi and Wilfred B Pugsley},
  journal={Lancet},
  year={1993},
  volume={342 8866},
  pages={276-7}
}
Ischaemic preconditioning (short periods of ischaemia with intermittent reperfusion) has been shown paradoxically to protect the myocardium from a subsequent longer ischaemic insult. The protection associated with preconditioning is one of the most powerful mechanisms of protection known and has been shown in every animal species investigated. However, there is no direct evidence that ischaemic preconditioning occurs in the human heart. We studied whether it was possible to precondition the… CONTINUE READING

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