Preconditioning strategies to limit graft immunogenicity and cold ischemic organ injury.

Abstract

During the transplant process, the graft is exposed to numerous events, which may enhance its immunogenicity. In particular, factors related to brain death, such as hemodynamic instability and systemic release of cytokines, cold preservation on harvesting, and reperfusion injury, are known to accumulate in harm, conveying a proinflammatory state to the… (More)
DOI: 10.1136/jim-52-05-32

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