Preconditioning preserves mitochondrial function and glycolytic flux during an early period of reperfusion in perfused rat hearts.

@article{Yabe1997PreconditioningPM,
  title={Preconditioning preserves mitochondrial function and glycolytic flux during an early period of reperfusion in perfused rat hearts.},
  author={Ken-ichi Yabe and Yoshihisa Nasa and Motohiko Sato and Raisuke Iijima and Satoshi Takeo},
  journal={Cardiovascular research},
  year={1997},
  volume={33 3},
  pages={677-85}
}
OBJECTIVE The purpose of the present study was to examine the effects of preconditioning on glycolysis and oxidative phosphorylation during reperfusion in perfused rat hearts. METHODS Preconditioning was induced by 5 min of ischemia and 5 min of reperfusion before 40 min of sustained ischemia and subsequent 30 min of reperfusion. Tissue energy metabolite levels, mitochondrial oxygen consumption capacity and adenine nucleotide translocator content of the perfused hearts were assessed at 40 min… CONTINUE READING