Preconditioning for cardioprotection against ischemia reperfusion injury: the roles of nitric oxide, reactive oxygen species, heat shock proteins, reactive hyperemia and antioxidants--a mini review.

@article{Miller2001PreconditioningFC,
  title={Preconditioning for cardioprotection against ischemia reperfusion injury: the roles of nitric oxide, reactive oxygen species, heat shock proteins, reactive hyperemia and antioxidants--a mini review.},
  author={M J Miller},
  journal={The Canadian journal of cardiology},
  year={2001},
  volume={17 10},
  pages={1075-82}
}
  • M J Miller
  • Published 2001 in The Canadian journal of cardiology
BACKGROUND In recent years, extensive studies have expanded the knowledge of the role of preconditioning (PC) for cardiac protection against ischemia reperfusion (I/R) injury. These studies are reviewed, and their relevance to the early and late phases of cardiac protection is discussed. CONCLUSIONS First, there is strong evidence that the L-arginine-nitric oxide pathway plays a major role in PC. Second, early and late phase protection are probably distinct phenomena with similar effects… CONTINUE READING

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