Preconception care and the risk of congenital anomalies in the offspring of women with diabetes mellitus: a meta-analysis.

@article{Ray2001PreconceptionCA,
  title={Preconception care and the risk of congenital anomalies in the offspring of women with diabetes mellitus: a meta-analysis.},
  author={Joel G. Ray and Tara E O'Brien and Wee Shian Chan},
  journal={QJM : monthly journal of the Association of Physicians},
  year={2001},
  volume={94 8},
  pages={435-44}
}
Offspring of women with pregestational diabetes mellitus are at increased risk for congenital malformations, largely attributable to poor periconceptional glycaemic control. We assessed the effect of preconception care in reducing congenital malformations, in a meta-analysis of published studies of preconception care in women with diabetes mellitus. Articles were retrieved from Medline (1970 to June 2000) and Embase (1980 to June 2000), and data abstracted by two independent reviewers. The… CONTINUE READING

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