Precocious loss of physiological sleep in a case of Creutzfeldt Jakob disease: a serial polygraphic study.

@article{Terzano1995PrecociousLO,
  title={Precocious loss of physiological sleep in a case of Creutzfeldt Jakob disease: a serial polygraphic study.},
  author={Mario G. Terzano and Liborio Parrino and Vladimiro Pietrini and Domenico Mancia and Maria Cristina Spaggiari and Giacomina Rossi and Fabrizio Tagliavini},
  journal={Sleep},
  year={1995},
  volume={18 10},
  pages={849-58}
}
Creutzfeldt-Jakob disease (CJD) is a prion-related subacute encephalopathy producing widespread neuronal degeneration and spongiform pathological changes, especially in the neocortex. Progressive dementia, motor signs and electroencephalographic (EEG) alterations characterize the full stage of the disease. A series of eight 24-hour polygraphic recordings were carried out in the last 3 months of life of a 68-year-old female patient affected by CJD that was confirmed neuropathologically. Genetic… CONTINUE READING