Precocious expression of Drosophila Rbp9 inhibits ovarian germ cell proliferation.

@article{Jeong2004PrecociousEO,
  title={Precocious expression of Drosophila Rbp9 inhibits ovarian germ cell proliferation.},
  author={Kyoungsuk Jeong and Jeongsil Kim-Ha},
  journal={Molecules and cells},
  year={2004},
  volume={18 2},
  pages={230-6}
}
We previously reported that Rbp9 is expressed in the germarium region as soon as germ cells complete mitosis and form 16 interconnected cystocytes. Mutation of Rbp9 caused over-proliferation of cystocytes and generated an ovarian tumor phenotype. This led us to conclude that Rbp9 either inhibits cell proliferation or is required for cell differentiation. To… CONTINUE READING