Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways.

Abstract

In the present study, we have evaluated the chemopreventive potential of geraniol (GOH), an acyclic monoterpene alcohol against ferric nitrilotriacetate (Fe-NTA) induced renal oxidative stress and carcinogenesis in Wistar rats. Chronic treatment of Fe-NTA induced oxidative stress, inflammation and cellular proliferation in Wistar rats. The chemopreventive… (More)
DOI: 10.1016/j.tox.2011.08.020

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