Preclinical evaluation of biotin labeling for red cell survival testing

@article{HoffmannFezer1997PreclinicalEO,
  title={Preclinical evaluation of biotin labeling for red cell survival testing},
  author={Gertrud Hoffmann-Fezer and C. Trastl and Wolfgang Beisker and Duglas Berg and Josef Obermaier and Wolfram Kessler and Josef Mysliwietz and Michael Schumm and Juliane Filser and Stefan Thierfelder},
  journal={Annals of Hematology},
  year={1997},
  volume={74},
  pages={231-238}
}
 Biotin labeling of red cells was tested in dogs as a preclinical study for cell survival. Red cells were labeled with either spacered Biotin-X-NHS (BxNHS) or water-soluble biotin compounds. After reinfusion, biotinylated red cells were detected in small blood samples (5 μl) with flow cytometry. Improved BxNHS labeling allows an easy detection of positive red cells for almost 100 days, whereas labeling with watersoluble compounds – despite strong labeling during the first days – results in a… CONTINUE READING
4 Citations
25 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Überlebenszeit transfundierter roter Blutkörperchen

  • H Vetter, L Veall
  • Urban & Schwarzenberg, Munich,
  • 1960
Highly Influential
4 Excerpts

The transfusion of red cells

  • PL Mollison, CP Engelfriet, M Contreras
  • Blood transfusion in clinical medicine,
  • 1994
2 Excerpts

Similar Papers

Loading similar papers…