Preclinical evaluation of Raman nanoparticle biodistribution for their potential use in clinical endoscopy imaging.

@article{Zavaleta2011PreclinicalEO,
  title={Preclinical evaluation of Raman nanoparticle biodistribution for their potential use in clinical endoscopy imaging.},
  author={Cristina L. Zavaleta and Keith Hartman and Zheng Miao and Michelle L. James and Paul Joseph Kempen and Avnesh Sinh Thakor and Carsten Haagen Nielsen and Robert Sinclair and Zhen Cheng and Sanjiv Sam Gambhir},
  journal={Small},
  year={2011},
  volume={7 15},
  pages={2232-40}
}
Raman imaging offers unsurpassed sensitivity and multiplexing capabilities. However, its limited depth of light penetration makes direct clinical translation challenging. Therefore, a more suitable way to harness its attributes in a clinical setting would be to couple Raman spectroscopy with endoscopy. The use of an accessory Raman endoscope in conjunction… CONTINUE READING