Preclinical and Clinical Evidence on Ipsilateral Corticospinal Projections: Implication for Motor Recovery

@article{Alawieh2017PreclinicalAC,
  title={Preclinical and Clinical Evidence on Ipsilateral Corticospinal Projections: Implication for Motor Recovery},
  author={Ali Alawieh and Stephen Tomlinson and DeAnna L Adkins and Steve A. Kautz and W Feng},
  journal={Translational Stroke Research},
  year={2017},
  volume={8},
  pages={529-540}
}

• Ali Alawieh, Stephen Tomlinson, +2 authors W Feng
• Published in Translational Stroke Research 2017
• DOI:10.1007/s12975-017-0551-5

Motor impairment is the most common complication after stroke, and recovery of motor function has been shown to be dependent on the extent of lesion in the ipsilesional corticospinal tract (iCST) and activity within ipsilesional primary and secondary motor cortices. However, work from neuroimaging research has suggested a role of the contralesional hemisphere in promoting recovery after stroke potentially through the ipsilateral uncrossed CST fibers descending to ipsilateral spinal segments… CONTINUE READING

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