Preclinical Study of the Effect of Cardiotropic Agents on Isolated Heart

@article{Goldshtein2004PreclinicalSO,
  title={Preclinical Study of the Effect of Cardiotropic Agents on Isolated Heart},
  author={Dmitry V Goldshtein and A. A. Zakaryan and Vladislav S. Kuzmin and Alexander G. Pogorelov and Galina S. Sukhova and E. V. Khrenova},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2004},
  volume={137},
  pages={566-567}
}
Direct effects of cardiotropic preparations on the hearts isolated from Wistar rats were examined. Deenergization of cardiomyocytes was modeled under conditions of hypoxic perfusion. Recovery of cardiac function during reperfusion was assessed by changes in the heart rate and contraction amplitude.