Preclinical Safety Evaluation Strategies of Gene Transfer Products: Regulatory and Technical Considerations

Abstract

Preclinical safety evaluation of gene transfer compounds is based on the strategy used for most new drugs and additionally includes certain aspects specific to biotechnology-derived products. Gene transfer compounds are most often composed of two entities: genetic material encoding a therapeutic protein, and a so-called vector, viral or non-viral, intended… (More)
DOI: 10.1007/PL00010012

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Cite this paper

@article{Christ2002PreclinicalSE, title={Preclinical Safety Evaluation Strategies of Gene Transfer Products: Regulatory and Technical Considerations}, author={Matthias Christ}, journal={Comparative Clinical Pathology}, year={2002}, volume={11}, pages={38-43} }