Preclinical Alzheimer's disease: diagnosis and prediction of progression

@article{Chong2005PreclinicalAD,
  title={Preclinical Alzheimer's disease: diagnosis and prediction of progression},
  author={M. Chong and S. Sahadevan},
  journal={The Lancet Neurology},
  year={2005},
  volume={4},
  pages={576-579}
}
BACKGROUND From the modest but important breakthroughs in the treatment of Alzheimer's disease (AD), diagnostic focus has increasingly shifted to the accurate detection of the earliest phase of the illness. The challenge of distinguishing preclinical AD from changes of normal ageing or established AD, has been recognised in several attempts at clinical classification. Of these attempts, Mayo Clinic's mild cognitive impairment (MCI) has received significant attention, although it has not been… Expand
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