Precision neutron diffraction structure determination of protein and nucleic acid components. VIII: the crystal and molecular structure of the β-form of the amino acidl-glutamic acid

  title={Precision neutron diffraction structure determination of protein and nucleic acid components. VIII: the crystal and molecular structure of the $\beta$-form of the amino acidl-glutamic acid},
  author={Mogens Steen Lehmann and Thomas F. Koetzle and Walter Clark Hamilton},
  journal={Journal of Crystal and Molecular Structure},
A neutron diffraction study of the β-form of L-glutamic acid, C5H9NO4, has been carried out. The structure is orthorhombic: space groupP212121,a= 5·159(5),b= 17·30(2),c= 6·948(7) Å andz = 4. Least-squares refinements based on 803 reflexions led to a final conventionalR value of 0·026, and bond lengths involving hydrogen atoms have been determined with an average precision of 0·004 Å. The molecule is in the zwitterion form, and no intramolecular hydrogen bonds have been found. The hydrogen atom… 
Precision neutron diffraction structure determination of protein and nucleic acid components. XVII. Molecular and crystal structure of the amino acid glycine hydrochloride
The amino acid salt glycine hydrochloride, H3N+⋅CH2⋅COOH⋅Cl−, crystallizes in the space group P21/c, a=7.117(2) A, b=5.234(2) A, c=13.745(3) A, β=97.25(1) °. The crystal structure has been refined
Structure of α Form of L-Glutamic Acid. α-β Transition
An X-ray analysis of the α form of L-glutamic acid, C5H9NO4, has been carried out. The space group is P212121 with a=7.068(1), b=10.277(1), c=8.755(1) A and Z=4. The structure was solved by the
X-Ray Crystal Structures of Amino Acids and Selected Derivatives
The past two decades have seen a tremendous increase both in the number and accuracy of amino acid, peptide, and protein crystal structure determinations. The recent strides made in computer and
The whole range of hydrogen bonds in one crystal structure: neutron diffraction and charge-density studies of N,N-dimethylbiguanidinium bis(hydrogensquarate).
Sensitive criteria such as the Laplacian of the electron density and energy densities in the bond-critical points reveal the incipient covalent character of the shortest O-H···O bond.
Hydrogen bonds in crystal structures of amino acids, peptides and related molecules.
  • S. Vinogradov
  • Chemistry, Biology
    International journal of peptide and protein research
  • 1979
The observed differences between the lengths of hydrogen bonds formed by different donor and acceptor groups in amino acids and peptides, imply differences in the energetics of their formation.
Crystal structures of amino acids: from bond lengths in glycine to metal complexes and high-pressure polymorphs
After the discovery of X-ray diffraction by crystals, amino acids were among the first organic compounds to have their solid-state structures investigated. The Cambridge Structural Database now
Unusual zwitterion of D,L-beta-carboxyaspartic acid: pKa and X-ray crystallographic measurements.
An investigation of the acidic properties and molecular structure of the new natural amino acid beta-carboxyaspartic acid (Asa) is described and analysis of the pKa data indicates that the predominate zwitterion in solution results from ionization of a beta- carboxyl group.
Analysis of O-H...O hydrogen bonds.
Some geometrical parameters associated with the donor and the acceptor end of O-H…O hydrogen bonds have been analysed and the main results are arrived at.


A Short, Slightly Asymmetrical, Intramolecular Hydrogen Bond: A Neutron Diffraction Study of Bis(2-amino-2-methyl-3-butanone Oximato )Nickel(II) Chloride Monohydrate {Ni(C 5H llN 20)2H} +CI- ·H20*
A neutron diffraction study of bis(2‐amino‐2‐methyl‐3‐butanone oximato)nickel(II) chloride monohydrate {Ni(C5H11N2O)2H}+Cl−·H2O has provided a wealth of precise information concerning the short
  • H. S. Simms
  • Biology
    The Journal of general physiology
  • 1928
Analysis of the experimental titration curves shows that gelatin contains acid groups with dissociation indices at pH 2.9 to 3.5 corresponding quantitatively with the content in dicarboxylic amino
A general theory of X‐ray diffraction in crystals
(1) To point out what I believe to be an error in his paper concerning the physics of diffraction in perfect crystals, and (2) to call to the attention of X-ray crystallographers certain aspects of
The Chemical Society
THE article which appears in NATURE, vol. xiv. p. 125, on the Organisation of the Profession of Chemistry throws doubt on the expediency of effecting the proposed organisation through the