Precision, signal-to-noise ratio, and dose optimization of magnitude and phase arterial input functions in dynamic susceptibility contrast MRI.

@article{Kotys2007PrecisionSR,
  title={Precision, signal-to-noise ratio, and dose optimization of magnitude and phase arterial input functions in dynamic susceptibility contrast MRI.},
  author={M. S. Kotys and Erbil Akbudak and Jennifer Lynn Markham and Thomas Edward Conturo},
  journal={Journal of magnetic resonance imaging : JMRI},
  year={2007},
  volume={25 3},
  pages={
          598-611
        }
}
PURPOSE To determine optimal conditions for precise measurement of arterial input function (AIFs) in dynamic susceptibility contrast (DSC) perfusion MRI. MATERIALS AND METHODS Magnitude-based (DeltaR(2)*) and phase-based (Deltaphi) AIFs were numerically simulated for several doses and baseline MRI noise levels [SNR(I(0))]. Random noise (1000 realizations) was added to real/imaginary MRI signals (derived from an internal carotid AIF), and AIF signal, noise, and signal-to-noise ratio (SNR) were… CONTINUE READING
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