Prebiotic Synthesis of Vitamin B6-type Compounds

@article{Austin2004PrebioticSO,
  title={Prebiotic Synthesis of Vitamin B6-type Compounds},
  author={S. Austin and T. G. Waddell},
  journal={Origins of life and evolution of the biosphere},
  year={2004},
  volume={29},
  pages={287-296}
}
  • S. Austin, T. G. Waddell
  • Published 2004
  • Chemistry, Medicine
  • Origins of life and evolution of the biosphere
  • Heating a dilute solution of NH3 and glycoaldehyde gives a large family of pyridines substituted with the same functional groups as occur in the forms of vitamin B6. Thus, vitamin B6-like molecules could have been present on the early Earth and could have been available for catalysis of primitive transamination reactions. Ethanolamine and N-methylethanolamine are also formed as major products. These are choline-like molecules, the latter of which is apparently formed by a prebiotic methylation… CONTINUE READING
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    References

    SHOWING 1-5 OF 5 REFERENCES
    The triose model: Glyceraldehyde as a source of energy and monomers for prebiotic condensation reactions
    • A. Weber
    • Medicine, Chemistry
    • Origins of life and evolution of the biosphere
    • 2005
    • 32
    Polyhydroxylated compounds in the Murchison meteorite?
    • G. Cooper
    • Chemistry
    • Origins of life and evolution of the biosphere
    • 2006
    • 2
    • Highly Influential
    Chemical Evolution of Carbohydrate Metabolism
    • 18
    "Biochemical Predestination" as Heuristic Principle for Understanding the Origin of Life
    • 4
    Interpretation of mass spectra of organic compounds
    • 526