Prebiotic Synthesis of Vitamin B6-type Compounds

  title={Prebiotic Synthesis of Vitamin B6-type Compounds},
  author={Sabrina M. Austin and T. G. Waddell},
  journal={Origins of life and evolution of the biosphere},
Heating a dilute solution of NH3 and glycoaldehyde gives a large family of pyridines substituted with the same functional groups as occur in the forms of vitamin B6. Thus, vitamin B6-like molecules could have been present on the early Earth and could have been available for catalysis of primitive transamination reactions. Ethanolamine and N-methylethanolamine are also formed as major products. These are choline-like molecules, the latter of which is apparently formed by a prebiotic methylation… Expand
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