Prebiotic Synthesis: Phosphorylation in Aqueous Solution

@article{Lohrmann1968PrebioticSP,
  title={Prebiotic Synthesis: Phosphorylation in Aqueous Solution},
  author={R. Lohrmann and L. Orgel},
  journal={Science},
  year={1968},
  volume={161},
  pages={64 - 66}
}
Formation of uridine-5'-phosphate from uridine and inorganic phosphate in aqueous solution is effected by the following condensing agents: cyanogen, cyanoformamide, cyanate, cyanamide, thioformate, ethylisocyanide, and a watersoluble carbodiimide. The yields are always small, even when a large excess of condensing agent is used. The cyclization of uridine-3'-(2')-phosphate occurs under the same conditions but in much greater yield. 
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  • 2
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  • 1972
  • 38
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  • 41
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  • Chemistry, Medicine
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...
1
2
3
4
5
...

References

SHOWING 1-10 OF 15 REFERENCES
Cyanamide Formation under Primitive Earth Conditions
  • 78
CYANAMIDE: A POSSIBLE KEY COMPOUND IN CHEMICAL EVOLUTION.
  • 82
  • PDF
Nucleotide Synthesis under Possible Primitive Earth Conditions
  • 91
Peptide Synthesis from Amino Acids in Aqueous Solution
  • 86
Motility of the Turtle Embryo, Chelydra serpentina (Linn�)
  • 71
Collection Czech
  • Chem. Commun
  • 1967
Science 148, 1221 (1965); J
  • Skoda and J. Moravek, Tetrahedron Letters 1966, 4167 (1966); J. Moravek and J. Skoda, Collection Czech. Chem. Commun. 32, 206 (1967); J. Moravek, Tetrahedron Letters
  • 1967
...
1
2
...