Preanesthetic train-of-four fade predicts the atracurium requirement of myasthenia gravis patients.

@article{Mann2000PreanestheticTF,
  title={Preanesthetic train-of-four fade predicts the atracurium requirement of myasthenia gravis patients.},
  author={Rose Mann and Manfred Blobner and S. Jelen-Esselborn and Raimund Busley and Christian Werner},
  journal={Anesthesiology},
  year={2000},
  volume={93 2},
  pages={346-50}
}
BACKGROUND The most sensitive diagnostic criterion of myasthenia gravis is a decrement in the muscular response to repetitive stimulation. The authors hypothesized that myasthenia gravis patients who show a train-of-four ratio (T4/T1) < 0.9 in the preanesthetic period will have increased sensitivity to nondepolarizing neuromuscular blocking agents compared with myasthenia gravis patients with preanesthetic T4/T1 > or = 0.9. METHODS After institutional review board approval was obtained, 20… CONTINUE READING

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Meretoja OA: Vecuronium dose-response and maintenance requirements in patients with myasthenia gravis

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