Preanalytical Stability of Antibodies to Pathogenic Antigens.

  title={Preanalytical Stability of Antibodies to Pathogenic Antigens.},
  author={Verity S Hodgkinson and Sam Egger and Fay Betsou and Tim Waterboer and Michael Pawlita and Angelika Michel and Mark S Baker and Emily Banks and Freddy Sitas},
  journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology},
  volume={26 8},
Background: Serologic testing for antibodies against epitopes from pathogens is a valuable tool for investigating the relationship between infection and disease. This study comprehensively evaluates the impact of preanalytic variation on antibody seropositivities to a selected set of antigens arising from delays in processing of blood samples, preprocessing storage temperature, and vacutainer type.Methods: We assessed peripheral blood collected from 29 volunteers in four different Vacutainer… CONTINUE READING


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