Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients.

@article{Ahmed2013PretreatmentRO,
  title={Pre-treatment role of inosine triphosphate pyrophosphatase polymorphism for predicting anemia in Egyptian hepatitis C virus patients.},
  author={Walaa H Ahmed and Norihiro Furusyo and Saad Zaky and Abeer Sharaf Eldin and Hany Aboalam and Eiichi Ogawa and Masayuki Murata and Jun Hayashi},
  journal={World journal of gastroenterology},
  year={2013},
  volume={19 9},
  pages={1387-95}
}
AIM To investigate and clarify, for the first time, the role of inosine triphosphate pyrophosphatase (ITPA) polymorphism in Egyptian chronic hepatitis C virus (HCV) patients. METHODS The human genomic DNA of all patients was extracted from peripheral blood cells in order to determine the single nucleotide polymorphism (SNP) of ITPA (rs1127354). SNP genotyping was performed by real time polymerase chain reaction (PCR, ABI TaqMan allelic discrimination kit) for 102 treatment-naive Egyptian… CONTINUE READING
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