Pre-synaptic kainate receptors in GABAergic and glutamatergic axon terminals in the monkey globus pallidus.

@article{KaneJackson2003PresynapticKR,
  title={Pre-synaptic kainate receptors in GABAergic and glutamatergic axon terminals in the monkey globus pallidus.},
  author={R Kane-Jackson and Yoland Smith},
  journal={Neuroscience},
  year={2003},
  volume={122 2},
  pages={285-9}
}
Although the localization and role of kainate receptors in the CNS remain poorly known, complex, and rather unusual, pre-synaptic auto- and heteroreceptor functions have been disclosed in various brain regions. Basal ganglia nuclei, including the globus pallidus, are enriched in GluR6/7 immunoreactivity. Using electron microscopic immunocytochemistry for GluR6/7 combined with post-embedding immunogold labeling for GABA, we demonstrate that GluR6/7 immunoreactivity is enriched in a large… CONTINUE READING