Pre-synaptic kainate receptor-mediated facilitation of glutamate release involves PKA and Ca(2+) -calmodulin at thalamocortical synapses.

Abstract

We have investigated the mechanisms underlying the facilitatory modulation mediated by kainate receptor (KAR) activation in the cortex, using isolated nerve terminals (synaptosomes) and slice preparations. In cortical nerve terminals, kainate (KA, 100 μM) produced an increase in 4-aminopyridine (4-AP)-evoked glutamate release. In thalamocortical slices, KA… (More)
DOI: 10.1111/jnc.12310

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@article{AndradeTalavera2013PresynapticKR, title={Pre-synaptic kainate receptor-mediated facilitation of glutamate release involves PKA and Ca(2+) -calmodulin at thalamocortical synapses.}, author={Yuniesky Andrade-Talavera and Paloma Duque-Feria and Talvinder S. Sihra and Antonio Rodr{\'i}guez-Moreno}, journal={Journal of neurochemistry}, year={2013}, volume={126 5}, pages={565-78} }